Medically reviewed by Alexander Tabibi, MD
July 24, 2021

In the ever-expanding world of cannabis exploration, one cannabinoid has been generating considerable buzz—THCV, short for Tetrahydrocannabivarin. With its chemical similarity to delta 9 THC and intriguing properties, THCV has captured the attention of both cannabis enthusiasts and researchers alike. In this complete guide, we delve into the question Does THCV get you high? We’ll explore the chemistry, potential psychoactivity, effects on the mind and body, medical applications, safety, legal status, and the future of THCV research.

This post is intended as information and for general knowledge only. It is not a substitute for medical advice, diagnosis, or treatment. It is recommended that you talk to a healthcare professional about this before introducing cannabinoids into your daily routine (especially if you have been diagnosed with any medical conditions or are under any medication). It is not recommended to drive or operate any machinery when using cannabis- or hemp-derived products. Use responsibly!

What Is THCV

THCV, or Tetrahydrocannabivarin, is a minor cannabinoid found within the cannabis plant. Its full chemical name, 3,5-dimethylheptyl-2,3,4,5-tetrahydrocannabinol, might sound complex, but its structure bears some resemblance to the more familiar delta 9 THC. However, it’s crucial to note the distinctions between them.

While both THCV and delta 9 THC interact with the endocannabinoid system, the subtle differences in their chemical structures lead to significant variations in their psychoactive effects. Delta 9 THC, the primary psychoactive component in cannabis, is renowned for its intoxicating effect, known as the “high.” In contrast, THCV tends to exhibit a different profile.

The Potential for Psychoactivity

Understanding THCV’s potential for psychoactivity necessitates a closer look at the endocannabinoid system, where it interacts with cannabinoid receptors—specifically, the CB1 and CB2 receptors. Unlike delta 9 THC, THCV does not bind strongly to CB1 receptors, which are primarily responsible for the psychoactive effects associated with cannabis. This weaker binding suggests that THCV is less likely to induce a typical cannabis-induced euphoria.

weed joint in hand

However, it’s essential to acknowledge that THCV’s psychoactivity can still be influenced by various factors, including dosage, individual differences, and interactions with other cannabinoids. Lower doses of THCV may be less likely to produce psychoactive effects, while higher doses may yield more noticeable changes in consciousness.

Individual differences in genetics and tolerance also play a role in how THCV affects each person. Some individuals may be more sensitive to THCV’s effects, while others may require higher doses to experience any noticeable changes.

Moreover, THCV’s interaction with other cannabinoids within the cannabis plant can impact its overall effects. The entourage effect, a phenomenon where the combined action of multiple cannabis compounds enhances their therapeutic potential, may play a role in modulating THCV’s effects.

THCV’s Effects on the Mind and Body

THCV’s effects extend beyond its psychoactivity. It can influence both the mind and body in unique ways.

In terms of physical effects, THCV has garnered attention for its potential as an appetite suppressant. Some studies suggest that THCV may help with weight management by reducing the urge to eat. This makes strains high in THCV, like Durban Poison and Red Congolese, particularly appealing to individuals seeking cannabis as part of their diet plan.

High, THCV, Tetrahydrocannabivarin

THCV is also regarded as a stimulant, promoting alertness and energy. Unlike the sedative effects of some other cannabinoids, THCV may help users stay focused and awake, making it a potential option for daytime use.

Additionally, THCV has been studied for its analgesic properties, which may offer relief from pain and discomfort.

On the mental front, THCV’s effects on mood and anxiety are of particular interest. Some users report that THCV strains have mood-enhancing properties and may help with anxiety disorders. However, more research is needed in this area to draw definitive conclusions.

Cognitively, THCV’s impact on memory and cognitive function is less clear compared to other cannabinoids like delta 9 THC. Some users claim it has minimal cognitive impairment, but more research is needed to substantiate these claims.

Medical and Therapeutic Uses

THCV’s potential medical applications have piqued the curiosity of researchers and healthcare professionals.

One of the most promising areas of research involves weight management. THCV’s appetite-suppressing effects could be a valuable tool in the fight against obesity and related health issues. By influencing appetite and metabolism, THCV may offer support to individuals aiming to shed excess pounds.

Furthermore, THCV has shown potential in managing type 2 diabetes. Research suggests that it may play a role in regulating blood sugar levels, which is crucial for those with diabetes. While this research is still in its early stages, it holds promise for future treatments.

In the realm of neuroprotection, THCV is being investigated for its ability to protect brain cells. This could have implications for conditions like Alzheimer’s disease and other neurodegenerative disorders.

Ongoing research and clinical trials continue to explore THCV’s potential applications. As new findings emerge, the medical community may embrace THCV-based treatments more widely.

Currently, THCV-based medications are limited in availability, but as research progresses, the market for THCV products is expected to expand.

Safety and Side Effects

Like any substance, THCV is not without potential side effects. Common adverse reactions may include anxiety, paranoia, and dry mouth. These effects can vary depending on the individual and the dose.

THCV’s interaction with other medications or substances should also be considered. It’s essential to consult with a healthcare professional if you are taking other medications or have concerns about potential interactions.

Long-term safety concerns related to THCV are not yet well-established due to limited research. As with many cannabis compounds, responsible usage guidelines are crucial to minimize potential risks. Users should start with low doses and gradually increase, ifneeded, to find their optimal dose.

The legal status of THCV varies from country to country. In some regions, THCV is classified as a controlled substance, while in others, it is less regulated. Individuals should be aware of the laws in their specific location before purchasing or using THCV products.

THCV products are available in various forms, including tinctures, edibles, and vape pens. Dispensaries in regions where cannabis is legal often carry a selection of THCV products. Additionally, online retailers may offer a range of options, allowing consumers to explore different THCV products.

However, regulations and restrictions can limit the availability of THCV products. It’s essential to research and source THCV products from reputable and legal sources to ensure quality and safety.

Conclusion

In conclusion, the question, “Does THCV get you high?” doesn’t have a straightforward answer. While THCV shares a chemical resemblance with delta 9 THC, its psychoactive effects are milder and influenced by various factors. Individual sensitivity, dosage, and interactions with other cannabinoids all play a role in determining the extent of THCV’s psychoactivity.