Delta 8 THC Drug Interactions

January 5, 2023
Weed And Drug Interactions (Delta 8)
Weed And Drug Interactions (Delta 8)

Delta 8 THC drug interactions have become increasing common since cannabis and specifically hemp and hemp-derived psychoactive cannabinoid products have become federally legal & their popularity has skyrocketed. While more research on the advantages certain cannabinoids and hemp derived CBD etc are showing promising results in ongoing studies – this means that many people are using e.g. Delta 8 THC without sufficient precautions. It should be remembered that though studies are promising – per the FDA – they are not conclusive and Delta 9 THC derived from cannabis remains federally illegal. 

Additionally it should be noted that much of the information in this article can most likely be applied to all the psychoactive hemp and cannabis derived cannabinoids. Therefore one should be cautions also with Delta 9, Delta 10 and 11, THCA, THCH, THCO, THCP, THCO, THCV, HHC etc.

Delta 8 THC Drug Interactions: Which medications interact?

Many people are surprised to learn that THC can negatively interact with certain medications, including:

  • Benzodiazepines;
  • Opioids;
  • Antidepressants;
  • Immunosuppressants;
  • Blood Pressure Medications;
  • Blood Sugar Medications.

Apparently, THC, like CBD, can suppress certain chemical reactions that might result in an increasing concentration of medication in your blood level. This may lead to intoxication. Some of these drugs may become dangerous if they are present in higher-than-normal amounts in the bloodstream.

THC may also produce some additive effects with certain medications, meaning that the effects of THC can add to the effects of other medications. Take benzodiazepines, for example. With both substances having sedative-like effects that suppress our nervous system, taking both THC and a benzodiazepine, such as Xanax or Valium, could cause the nervous system to slow down to such an extent that the person will feel extremely drowsy. This could be especially dangerous if, say, a person is driving.

What We Know About Delta 8, and What We Don’t?

CBD has been widely popular for well over a decade at this point, which means that we have been able to study it intensively for over ten years. As a result, we have a good deal of information about the exact mechanisms that are at work when we consume CBD in terms of how it is utilized and metabolized by the body.

Delta 8 has the unfortunate circumstance of simply being too new for there to be an enormous wealth of research behind it compared to what we have with cannabidiol. This means that we have yet to see any studies about delta 8 and prescription drugs specifically.

It is safe to assume that as time passes and delta 8 continues to grow in popularity, researchers will discover more about it, including its interaction with other medications. For now, we can only assume how delta-8 THC will behave in our body by comparing it to a similar cannabinoid.

How to Safely Maintain a Delta 8 Routine While on a Prescription Medication?

So, because we cannot say for sure the effects delta 8 has on prescription drugs, it is essential to be as cautious as possible. Here are some tips that will help you achieve that.

Tip #1: Talk to Your Doctor

First, it is strongly advised to consult your doctor or healthcare provider about combining delta-8 and other medications. Ask your doctor about the possible delta 8 – drug interaction, and ensure they are up to date on current research about delta-8 THC.

Tip #2: Start with a Low Dose of Delta 8

If you are taking medication and have your doctor’s approval to begin a delta 8 routine, start with a low dose to avoid severe interaction. After monitoring how you feel, you can consider increasing your dosage.

Tip #3: Do not Take Them Simultaneously

It may be best not to take delta 8 at the same time as your medication. For instance, if you take your medication in the morning, take your delta 8 during the evening hours. This way, you can avoid both of the substances concentrating in your bloodstream simultaneously, which would theoretically put you at the most risk of interaction.

Tip #4: Monitor the Effects Carefully

Make sure to monitor how you feel when combining your meds and delta 8, and seek medical help if you have any concerns about the side effects.

Tip #5: Avoid Grapefruit

It may be surprising to you, but grapefruit can significantly interfere with your body’s ability to metabolize medications. Thus, it is better to restrain eating it for a while.

Tip #6: Avoid Alcohol

Alcohol is known to interact with many medications, so avoid drinking alcohol if you are already taking both delta-8 and a prescription drug.

While there is a lot that we do not know about delta-8 THC, it is better to be a bit more cautious rather than regret your choices. If you are taking prescription medications, talk to your doctor prior to starting a delta-8 routine. While delta 8 is relatively safe overall, you need to ensure that it will not interact with a drug you are presently taking.