THC-P vs. Other Cannabinoids

September 20, 2021
THC-P Cannabinoid versus
THC-P Cannabinoid versus

It really has been quite a year for the hemp industry, as 2021 has seen a dazzling number of “new” cannabinoids make their way onto the scene, all with their own distinctive effects and incredible uses.  Now, we have Tetrahydrocannabiphorol (THC-P), a cannabinoid already showing to have some pretty phenomenal effects that make it worth trying out. 

THC-P is remarkably new, in terms of our understanding of it.  What this means is that we know little about its full scope compared to our understandings of other, more prominent cannabinoids like cannabidiol (CBD), cannabigerol (CBG), cannabinol (CBN), and delta-9-tetrahydrocannabinol (delta-9 THC).  Because of how new it is to the scene, it’s understandable that people want to learn more about it before they try it. 

How Does THC-P Actually Stack Up Against Other Cannabinoid Types?

To paint a better picture of what we know about tetrahydrocannabiphorol so far, it’s best to compare it to other, more well-known cannabinoids, in order to then understand how it measures up.

#1: Capable of Getting You High

When tetrahydrocannabiphorol was first analyzed, it was found that this compound is about 30x more capable of attaching itself to CB1 receptors responsible for the psychoactive response.  Meaning, THC-P might be far more psychoactive than delta-9 THC, let alone delta-8-Tetrahydrocannabinol (delta-8 THC), delta-10-tetrahydrocannabinol (delta-10 THC), tetrahydrocannabinol (THC-O), tetrahydrocannabivarin (THCV), and even hexahydrocannabinol (HHC), which are all minorly psychoactive cannabinoids.  While we don’t have much information about the specifics of its high due to the fact that it’s not yet a widely available cannabinoid, and therefore we haven’t heard from real users what it’s capable of, we can tell you that if you do take it, you should expect a powerful high.  Probably is best suited then for experienced THC users who already have some level of tolerance to these effects.

At the same time, there are plenty of cannabinoids many of us take that aren’t psychoactive at all – mainly CBD, CBG, and CBN.

How THC-P Compares to Other Cannabinoids

  • THC-P: Potentially 30 times as psychoactive as delta 9
  • CBD: Not psychoactive
  • CBN: Not psychoactive
  • CBG: Not psychoactive
  • Delta 8: About 70% as psychoactive as delta 9 THC
  • Delta 9: Default psychoactive (moderate to high)
  • Delta 10: About 70% as psychoactive as delta 9 THC
  • THCV: Mildly psychoactive at certain doses
  • THC-O: About 3 times as psychoactive as delta 9
  • HHC: Probably as psychoactive as delta 9

#2: How Much is Produced in Hemp

Tetrahydrocannabiphorol is a naturally occurring cannabinoid in the hemp plant.  Despite how new it is to our awareness; it’s always existed in the plant material.  One reason why we never knew about it is because it’s a very trace cannabinoid, that exists in an even lower amount in the plant than delta-9 THC.  Of course, because of today’s advanced extraction methods, we can take it in higher concentrations that allow us to really feel its effects.

THC-P occurs in lower amounts than any cannabinoids that are presently on the market, though the exact amount is currently unknown by the general public as this has not been disclosed.  We know that CBD is the most dominant cannabinoid in hemp, making up between 15 to 20% of the plant’s chemical composition on average, with CBN, CBG, and CBC being present in much lower amounts.  Delta 8 THC is found in about 0.1% of hemp, and THC-P likely makes up even less than that.  Note that we can’t compare this to delta 10 THC or THC-O, which are both synthesized from the hemp plant in some way or another, rather than existing naturally in the plant’s compound makeup.

How THC-P Compares to Other Cannabinoids

  • THC-P: Probably less than 0.1%
  • CBD: 15-20%
  • CBN: Less than 1%
  • CBG: About 1%
  • Delta 8: Less than 0.1%
  • Delta 9: 0.3%
  • Delta 10: Not naturally occurring
  • THCV: Probably about 0.1%
  • THC-O: Not naturally occurring
  • HHC: Unknown

#3: When It Was Discovered

Tetrahydrocannabiphorol was discovered in December of 2019, by a team of Italian researchers who used advanced methods to isolate the cannabinoids of the hemp plant.  Compare this to many of the other cannabinoids that have been tried, like CBD, delta-8, and THCV, which we have actually known about for decades, despite them only being legal in recent years. 

How THC-P Compares to Other Cannabinoids

  • THC-P: December of 2019
  • CBD: 1940
  • CBN: 1899
  • CBG: 1964
  • Delta 8: 1965
  • Delta 9: 1964
  • Delta 10: 2020
  • THCV: 1973
  • THC-O: Sometime between 1949-1970
  • HHC: Unknown

#4: How Much We Know About It

Because of how new tetrahydrocannabiphorol is in terms of its discovery, so far, there is next to no research on its effects.  All that we have is one study that was provided by the same team of researchers who discovered the cannabinoid.  Meanwhile, we have decades’ worth of research when it comes to other mainstream cannabinoids, which allows us to really understand what these compounds are capable of, and how they interact with the body. 

We can say that THC-P’s popularity is about to really take off, and there is a lot of funding going into researching cannabis right now due to more cannabis-friendly laws and industries that revolve around the therapeutic uses of cannabinoids.  So, it will be researched quite a bit in the following years, almost certainly.  And, we cannot wait to learn more about what this compound is capable of.  But, many people are still wishing there was more research behind it, since we are so used to being able to access years’ worth of data on most cannabinoids.

How THC-P Compares to Other Cannabinoids

  • THC-P: One study so far
  • CBD: Ample studies available
  • CBN: Moderate number of studies available
  • CBG: Moderate number of studies available
  • Delta 8: Small number of studies available
  • Delta 9: Ample studies available
  • Delta 10: No studies available
  • THCV: Moderate number of studies available
  • THC-O: Almost no studies available
  • HHC: Almost no studies available

#5: Potential Properties It Can Provide

Like we said, the research on tetrahydrocannabiphorol is limited.  We still don’t know the full potential of what this cannabinoid can do when it comes to its individual properties.  We do know that THC-P is a cannabinoid, and therefore offers its properties by binding to cannabinoid receptors throughout the body to regulate different bodily processes, which is something that all cannabinoids are capable of.

The one study that we do have provides us a decent idea of some if its effects.  The researchers who analyzed THC-P noticed that the cannabinoid shares many properties in common with delta-9 THC and CBD, only these properties seem to be more potent, again because of how it attaches itself to cannabinoid receptors. 

Mainly, THC-P seems to be associated with effects on mood, appetite, pain and nausea, but there’s no doubt that there are many other properties that still haven’t been discovered that can be very useful to the human body. 

Note: Delta-8 and delta-10 both seem to offer these properties in milder amounts, due to being mildly acting cannabinoids by nature.  THCV stands out as it seems to reduce appetite while the others mentioned, including THC-P, seem to potentially increase appetite.

How THC-P Compares to Other Cannabinoids

  • THC-P: psychoactive, appetite, mood, pain, nausea
  • CBD: mood, sleep, pain, digestion, nausea, nervous system function, neurological function, inflammation, energy
  • CBN: mood, sleep
  • CBG: inflammation, pain, nausea, glaucoma
  • Delta 8: psychoactive, mood, sleep, pain, nervous system function, appetite, nausea, inflammation
  • Delta 9: psychoactive, nausea, pain, neurological function, inflammation, sleep, appetite, nervous system function
  • Delta 10: psychoactive, mood, energy
  • THCV: psychoactive at moderate to high doses, blood sugar, weight, appetite (suppressant), mood
  • THC-O: strong psychoactive
  • HHC: psychoactive, mood, pain, nausea, appetite; probably similar to the properties of delta 9 THC due to their structural similarity

#6: How Easy it is to Purchase

As tetrahydrocannabiphorol was only discovered a little less than 2 years ago, it took quite a bit of time for manufacturers of hemp products to develop practical means for isolating, extracting and concentrating the cannabinoid to produce THC-P products.  Therefore, availability of THC-P formulas is extremely limited for the time-being, but that could very well change within the next year as demand begins to grow.  THC-P should come in the same product types that we’re all familiar with by now, such as vape carts, disposable vapes, gummies, and the like. 

You can compare this to other cannabinoids which are widely available on today’s market, dominated primarily by CBD and delta 8, although recently inclusive of other cannabinoids like CBN, CBG, and delta 10.

How THC-P Compares to Other Cannabinoids

  • THC-P: Not yet widely available
  • CBD: Widely available
  • CBN: Relatively available
  • CBG: Relatively available
  • Delta 8: Widely available
  • Delta 9: Widely available in states in which marijuana is legal
  • Delta 10: Somewhat available
  • THCV: Somewhat available
  • THC-O: Somewhat available
  • HHC: Somewhat available

The Winner Here: Split Decision

There is still a lot to learn about tetrahydrocannabiphorol in terms of the specifics of its properties, but what we already do know is that it’s clearly a one-of-a-kind cannabinoid that performs in ways that are far more powerful than many others that we’re used to, thanks to its exceptional efficiency when it comes to binding to cannabinoid receptors.  Now that THC-P is becoming available, you can see for yourself what properties it can offer compared to those of other popular cannabinoids in the hemp plant.