Medically reviewed by Alexander Tabibi, MD
October 12, 2023

In the ever-evolving landscape of the cannabis industry, the choice between different strains can be as varied as the effects they offer. Two intriguing options that have gained popularity among cannabis enthusiasts are the Devil’s Lettuce strain and the Laughing Buddha strain. Each has its unique characteristics and effects, making it essential for consumers to have a comprehensive understanding of what they entail before making a choice. In this comparative guide, we’ll delve into the origins, appearance, aroma, cannabinoid profiles, effects, medical applications, growing characteristics, popularity, consumer reviews, legal status, and considerations surrounding Devil’s Lettuce and Laughing Buddha strains.

This post is intended as information and for general knowledge only. It is not a substitute for medical advice, diagnosis, or treatment. It is recommended that you talk to a healthcare professional about this before introducing cannabinoids into your daily routine (especially if you have been diagnosed with any medical conditions or are under any medication). It is not recommended to drive or operate any machinery when using cannabis- or hemp-derived products. Use responsibly!

Origins and Genetics

Devil’s Lettuce Origins

Devil’s Lettuce, often associated with its strong Californian roots, boasts a genetic lineage that can be traced back to iconic strains like OG Kush and Blue Dream. This hybrid’s popularity can be partly attributed to its illustrious origins.

Laughing Buddha Origins

In contrast, Laughing Buddha takes a journey across continents to its origins. This predominantly sativa strain has its roots in Thai and Jamaican landrace strains, lending it a unique genetic profile that has piqued the interest of cannabis aficionados worldwide.

When it comes to breeders and cultivators, both strains have seen various individuals and seed banks contribute to their propagation, further solidifying their presence in the cannabis market.

Appearance and Aroma

Devil’s Lettuce

Devil’s Lettuce showcases dense, forest-green buds adorned with fiery orange hairs, creating an enticing visual appeal. Its aroma is a complex blend of pungent earthiness with subtle hints of citrus and pine. This combination of appearance and aroma is sure to intrigue the senses of any cannabis connoisseur.

Laughing Buddha

In contrast, Laughing Buddha presents itself with bright-green, fluffy buds accented by striking red and orange hairs. Its aroma, on the other hand, is a delightful blend of sweetness and fruitiness, often accompanied by subtle spicy notes. The vibrant appearance and enticing fragrance of Laughing Buddha make it a compelling choice for those seeking a sensorial experience.

Cannabinoid Profile

Devil’s Lettuce

In terms of cannabinoid content, Devil’s Lettuce frequently features high THC levels, which can vary depending on the specific phenotype. This high THC content contributes to its reputation for delivering potent psychoactive effects. Additionally, Devil’s Lettuce may have moderate CBD levels, offering potential therapeutic benefits alongside its recreational appeal.

Laughing Buddha

Laughing Buddha also leans towards a high THC content, providing users with an uplifting and euphoric experience. Its THC levels are generally robust, making it a go-to choice for those seeking a cerebral and mood-enhancing high. Like Devil’s Lettuce, Laughing Buddha may contain trace amounts of CBD, though not as prominently.

Comparing the terpene profiles of these two strains can further enhance our understanding of their flavors and effects, with each strain offering a unique combination of aromatic compounds.

Effects and Usage

Devil’s Lettuce

Devil’s Lettuce typically induces a relaxing, euphoric sensation that can stimulate creativity. Its effects are well-suited for evening relaxation or engaging in artistic endeavors. Whether you’re seeking relief from stress or simply looking to unwind, Devil’s Lettuce has something to offer.

Laughing Buddha

Laughing Buddha lives up to its name by eliciting laughter, happiness, and an energizing buzz. This strain is an excellent choice for social gatherings or daytime activities where a boost of positivity and energy is desired. Its effects can be likened to a warm burst of sunshine on a gloomy day.

Medical Applications

Devil’s Lettuce

Medical users often turn to Devil’s Lettuce for its potential pain-relieving properties, stress management capabilities, and effectiveness in treating insomnia. While scientific studies continue to explore its therapeutic potential, numerous individuals have reported positive outcomes when using this strain to alleviate various ailments.

Laughing Buddha

Laughing Buddha offers a unique set of therapeutic applications, such as mood enhancement, anxiety reduction, and fatigue alleviation. Many users have found relief from conditions related to anxiety and depression, thanks to its uplifting effects. Though anecdotal, these experiences underline its potential as a medicinal cannabis strain.

Growing Characteristics

Devil’s Lettuce

Cultivating Devil’s Lettuce requires attention to detail. Growers can choose between indoor and outdoor cultivation, with indoor environments offering greater control over factors like humidity and temperature. Proper care is essential to maintain the strain’s distinctive aroma and flavor throughout the growing process.

Laughing Buddha

Laughing Buddha is known for its adaptability to various growing conditions, making it a suitable choice for both novice and experienced cultivators. However, it’s important to note that this strain may be susceptible to pests or mold in certain environments. Proper care and monitoring are key to a successful harvest.

Popularity and Availability

Devil’s Lettuce

Devil’s Lettuce has made a significant mark in the cannabis market, particularly in its home state of California. Its popularity extends beyond state lines, with dispensaries in New York, Canada, and even as far as Australia offering this sought-after strain to cannabis enthusiasts.

Laughing Buddha

Laughing Buddha’s appeal extends globally, making it a popular choice not only in its native regions but also in countries like Spain, where it has gained a considerable following. Its reputation for delivering uplifting and joyful effects has contributed to its widespread availability.

Consumer Reviews and Recommendations

Devil’s Lettuce

User reviews of Devil’s Lettuce often highlight its relaxing properties, making it a go-to option for unwinding after a long day. Consumers recommend it for its potential to ease pain and stress, and some even praise its creative-inducing qualities. The strain’s versatility means it can cater to a variety of preferences and needs.

Laughing Buddha

Consumers who have experienced Laughing Buddha consistently mention its mood-enhancing effects and the infectious laughter it induces. Many recommend it for social situations, as it can uplift the spirits and promote lively interactions. If you’re in search of a strain that brings joy and positivity, Laughing Buddha may be your ideal choice.

Before making a choice between Devil’s Lettuce and Laughing Buddha, it’s crucial to consider the legal status of these strains in your region or country. The legalization of cannabis varies widely across the globe, and adherence to local laws and regulations is of utmost importance.

Making Your Choice

In summary, Devil’s Lettuce and Laughing Buddha are two distinct cannabis strains, each with its own set of characteristics and effects. Devil’s Lettuce leans towards relaxation and creativity, making it a suitable choice for evening use and stress relief. On the other hand, Laughing Buddha shines with its uplifting and euphoric properties, ideal for daytime activities and enhancing mood. When making your choice, consider your preferences, goals, and the legal status in your area to ensure a responsible and enjoyable cannabis experience.

In the ever-expanding world of cannabis strains, Devil’s Lettuce and Laughing Buddha are just a glimpse of the variety available to consumers. Explore these strains responsibly, and remember to stay informed about the latest news and developments in the cannabis industry. Whether you opt for the Devil’s Lettuce or Laughing Buddha, may your journey in the world of Mary Jane be a fulfilling and enlightening one.