Medically reviewed by Alexander Tabibi, MD
September 17, 2023

Mac 1 and Guava strains have gained immense popularity among cannabis consumers in recent years. These two strains, known for their unique flavor profiles and potent effects, have captured the attention of strain enthusiasts and flavor chasers alike. In this article, we will conduct an in-depth comparison of Mac 1 and Guava strains, shedding light on their origins, appearance, aroma, flavor, cannabinoid and terpene profiles, effects, medical benefits, growing difficulty, yield, popularity, and availability.

This post is intended as information and for general knowledge only. It is not a substitute for medical advice, diagnosis, or treatment. It is recommended that you talk to a healthcare professional about this before introducing cannabinoids into your daily routine (especially if you have been diagnosed with any medical conditions or are under any medication). It is not recommended to drive or operate any machinery when using cannabis- or hemp-derived products. Use responsibly!

Overview of Mac 1 Strain and Guava Strain

The Mac 1 strain, also known as Miracle Alien Cookies, is an indica-dominant hybrid. It is a result of crossing Alien Cookies with a hybrid of Starfighter and Columbian. On the other hand, the Guava strain, often referred to as Guava Kush, is a cross between the popular Blue Dream and the indica-dominant strain, Purple Punch. Both strains boast impressive genetics, making them stand out in the diverse world of weed strains.

Appearance and Aroma

Mac 1 buds typically exhibit a vibrant lime-green color and are densely packed with trichomes, giving them a frosty appearance. Guava buds, on the other hand, lean towards darker shades of green with striking orange pistils. When it comes to aroma, Mac 1 is known for its pungent and earthy scent, while Guava offers a delightful blend of citrus and tropical fruit fragrances that tantalize the senses.

Flavor Profile

Smoking or vaping Mac 1 provides a smooth and creamy taste with subtle hints of cookies and cream. In contrast, Guava brings a burst of fruity flavors with distinct notes of guava and berries, making it a favorite among those who enjoy a sweeter taste in their cannabis experience.

Cannabinoid and Terpene Profile

Mac 1 is celebrated for its high THC content, often reaching levels well above 20%. In comparison, Guava tends to have a more balanced THC to CBD ratio, making it appealing to medical cannabis users seeking relief without overwhelming psychoactive effects. Terpenes such as myrcene, limonene, and caryophyllene are prevalent in both strains, contributing to their distinct effects and aroma.

Effects and Medical Benefits

Mac 1 is known for inducing a powerful euphoria and providing a motivational boost, making it an excellent choice for creative minds and individuals seeking an energy lift. Guava, on the other hand, offers a relaxing high that can melt away stress and anxiety, making it a great option for those in need of calm and tranquility. Medical cannabis patients may find relief from conditions such as insomnia, anxiety, and chronic pain with these two strains.

Growing Difficulty

Mac 1 is notorious for being a demanding strain to grow, requiring precise environmental conditions and experienced cultivation techniques. On the contrary, Guava is relatively more forgiving and suitable for novice growers who seek to cultivate their cannabis at home.

Yield and Flowering Time

Mac 1 is notorious for its moderate to low yield, making it a challenge for commercial growers seeking high returns. In comparison, Guava boasts a decent yield, making it more attractive to those looking to maximize their production.

Popularity and Availability

Both Mac 1 and Guava strains have garnered a dedicated following of cannabis enthusiasts, but their availability may vary depending on the region. While some dispensaries may carry both strains, others may have limited access to them due to their popularity.

Which Strain is Right for You

Choosing between Mac 1 and Guava strains depends on individual preferences and desired effects. If you seek an invigorating and motivating experience, Mac 1 might be the perfect choice. However, if relaxation and calm are what you crave, Guava could be your ideal companion. Remember always to consume cannabis responsibly and be mindful of your local laws and regulations.


Mac 1 and Guava strains offer a diverse range of characteristics, effects, and flavors for cannabis consumers to explore. Whether you are a seasoned cannabis enthusiast or a medical cannabis patient, understanding the nuances of each strain can help you make informed decisions that align with your preferences and medical condition. As the world of cannabis continues to evolve, these two strains will undoubtedly remain a favorite among weed connoisseurs and enthusiasts for years to come. Happy smoking, and may your cannabis journey be filled with relaxation, euphoria, and motivation.