Medically reviewed by Alexander Tabibi, MD
October 1, 2023

CBD vs. Delta-8: two compounds gaining increasing popularity in the health and wellness industry. CBD, short for Cannabidiol, is a non-psychoactive cannabinoid extracted from hemp and marijuana plants. It interacts with the endocannabinoid system, which regulates various physiological processes. On the other hand, Delta-8 THC, or Delta-8 Tetrahydrocannabinol, is a cannabinoid with mild psychoactive properties, derived from the same plants as CBD. In this article, we will delve into the differences between these compounds, their potential benefits, and safety considerations, aiming to provide a thorough comparison of CBD and Delta-8.

This post is intended as information and for general knowledge only. It is not a substitute for medical advice, diagnosis, or treatment. It is recommended that you talk to a healthcare professional about this before introducing cannabinoids into your daily routine (especially if you have been diagnosed with any medical conditions or are under any medication). It is not recommended to drive or operate any machinery when using cannabis- or hemp-derived products. Use responsibly!

What is CBD?

CBD, one of over 100 cannabinoids found in cannabis plants, is primarily extracted from hemp, which contains a lower concentration of THC compared to marijuana. It interacts with CB1 and CB2 receptors in the endocannabinoid system, potentially affecting pain modulation and reducing inflammation. CBD comes in various product forms, such as oils, gummies, and topicals, with differences in bioavailability and onset of effects.

The therapeutic benefits of CBD are supported by scientific research, particularly in managing conditions like epilepsy, anxiety disorders, and chronic pain. While CBD is generally recognized as safe and non-intoxicating, it may cause mild side effects such as drowsiness and dry mouth, along with possible interactions with medications.

What is Delta-8?

Delta-8 THC, a naturally occurring minor cannabinoid in cannabis plants, is extracted from hemp and can be converted from CBD. It differs from Delta-9 THC, the psychoactive component in cannabis, in terms of chemical structure and potency. Due to its distinction from Delta-9 THC, Delta-8 THC has a potentially more favorable legal status.

Delta-8 products come in various forms, including vape cartridges, edibles, and tinctures, and have gained popularity among users seeking mild psychoactive effects. However, the safety of Delta-8 THC remains a subject of limited research, and reported side effects may include increased heart rate and potential cognitive impairment.

CBD vs. Delta-8

Effects and Differences

CBD and Delta-8 exert different effects on the body and mind. While CBD offers relaxation and stress reduction without causing intoxication, Delta-8 THC can produce a mild “high” in some users due to its psychoactive properties. These compounds interact differently with the endocannabinoid system, leading to distinct effects and potential therapeutic uses.

Unlike CBD’s non-psychoactive nature, Delta-8 THC possesses mild psychoactive properties, which can impact cognitive abilities. The onset and duration of effects also differ between CBD and Delta-8 products based on the method of consumption, making them more suitable for different situations.

User experiences and anecdotal evidence further highlight the subjective differences between CBD and Delta-8. Individual preferences and responses play a significant role in shaping the choice between these compounds.

Potential Uses and Applications

Both CBD and Delta-8 THC have shown potential therapeutic benefits, although they are often used for different purposes. CBD is commonly utilized for anxiety, pain, and insomnia, with clinical studies supporting its efficacy in managing these conditions. Delta-8 THC, on the other hand, is known for its antiemetic properties, potentially providing relief from nausea, and appetite stimulation, which could be beneficial for those struggling with reduced appetite.

Comparing their effectiveness in managing various health conditions, CBD and Delta-8 THC exhibit strengths in different areas based on available research and anecdotal evidence. Ongoing studies are continuously exploring the potential benefits of both compounds, shedding light on their therapeutic potential for various medical conditions.

Legality and Regulations

The legal status of CBD products differs based on whether they are derived from hemp or marijuana. CBD derived from hemp (containing less than 0.3% THC) is generally legal under the 2018 Farm Bill. However, CBD derived from marijuana may be subject to stricter regulations due to its higher THC content.

Delta-8 THC faces unique legal challenges due to its psychoactive properties and the evolving legal landscape surrounding cannabinoids. Different states may have varying regulations for Delta-8 products, and ongoing discussions may impact its legal status in the future.


In conclusion, CBD and Delta-8 are two distinct cannabinoids derived from hemp and marijuana plants, each offering unique effects and potential benefits. CBD, with its non-psychoactive nature and diverse therapeutic applications, is widely used for various health conditions. On the other hand, Delta-8 THC’s mild psychoactive properties make it popular among users seeking a controlled, intoxicating effect.

As the research on these compounds continues to expand, more insights into their therapeutic potential, safety considerations, and regulatory status will emerge. It is essential for consumers to stay informed about the latest developments to make well-informed decisions regarding their use of CBD and Delta-8 products. As with any cannabis product, it is advisable to consult with a healthcare professional before incorporating them into a medical or wellness regimen, particularly if one has a medical condition or is taking medications.


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Delta-9-THC Effects: Understanding the Impact of Tetrahydrocannabinol on the Body and Mind