Marijuana and Medication Interactions

August 15, 2020
Meds and Weed Combine
Meds and Weed Combine

Should I be aware of any Marijuana and Medication Interactions?

Whether you’re taking marijuana for medical or recreational purposes, it’s always important to understand and discuss the potential dangers of any interactions these might have with each other. (This is true for ANY combination of products, including prescription and over the counter products or supplements you take.) Research study on just how cannabis disrupts other medicines is limited. However, has a list of 24 products that might have marijuana and medication interactions.

These include

  • alfentanil
  • buprenorphine
  • butorphanol
  • codeine
  • dezocine
  • fentanyl
  • hydrocodone
  • hydromorphone
  • levomethadyl acetate
  • levorphanol
  • meperidine
  • methadone
  • morphine
  • morphine liposomal
  • nalbuphine
  • oxycodone
  • oxymorphone
  • pentazocine
  • propoxyphene
  • remifentanil
  • sodium oxybate
  • sufentanil
  • tapentadol
  • tramadol

You should review all the medications you are taking with your doctor or your dispensary. Additionally you can visit for a list of medications that have minor and moderate intractions with cannabis. You can find further information on each specific medication.

It’s important to remember that drugs, including prescription medications, supplements, and natural remedies, including medical marijuana, CBD, or even alcohol, interact with each person and situation differently, so you need to pay close attention to your own reactions and be open and honest with your medical professional.

Cannabis is also known for certain side effects, which again vary by person. They typically include dry mouth or “cotton mouth”, and dry eyes, so it’s always important to stay hydrated. These will be exacerbated if other medications or dietary supplements you take are also known to have dehydrating effects.

For some, cannabis can increase or trigger paranoid thinking or increase anxiety. This is usually related to the onset speed or uncertainty of effects as a novice user or increased intake. In some instances, and with some strains, these can be attributed to a heightened state of mind or existing mood.


Talk to your doctor, be informed, and be aware of your own reaction. Take it slow.